Repairing a Broken Heart

When both the left and right ventricles of your heart are damaged, only a donor heart transplantation, or a replacement heart can save your life.

The AbioCor Implantable Replacement Heart is designed for patients whose hearts have suffered irreparable damage to both ventricles. During the past six months heart patients in the USA have been given on of these totally artificial hearts as part of clinical trials.

How do these replacement "hearts" work and how do they differ from natural hearts?

ABIOCOR IMPLANTABLE REPLACEMENT HEART PROCEDURE PERFORMED AT JEWISH HOSPITAL BY UNIVERSITY OF LOUISVILLE SURGEONS

Louisville Jewish Hospital and the University of Louisville announced today...the world's first implantation of ABIOMED, INC's AbioCor Implantable Replacement Heart, on Monday, July 2. ...The patient is resting comfortably.

The AbioCor™ Implantable Replacement Heart is intended as a substitute for severely diseased human hearts in patients suffering from coronary heart disease.

When these patients are at risk of death, the AbioCor is designed to both extend life and provide a reasonable quality of life.

After implantation, the device does not require any tubes or wires to pass through the skin. Power to drive the prosthetic heart is transmitted across the intact skin.

AbioCor Implantable Replacement Heart
with permission from AbioCor

Click here for Interactive Diagram of the AbioCor Replacement Heart (New Window)

How does the heart work?

The four chambers of the heart are each made of cardiac muscle which contracts automatically, powerfully and without tiring as fast as 3 times per second for up to 100 years. The energy for a natural heart comes from respiration. The release of energy from glucose using oxygen, to make carbon dioxide and water. The glucose and the oxygen are carried to the heart in the blood, through the coronary artery (see photo below).

natural heart
Natural heart. A coronary artery and vein are clearly visible.

 

Coronary heart disease prevents the supply of blood to the heart muscle and it stops pumping.

Two hearts as one

In the natural hearts of all birds and mammals the blood flows separately through the two sides. In effect there are two pumps. Each pump is made from two heart chambers:

  1. An Atrium, which collects blood from the veins and pumps it into the ventricle.
  2. A Ventricle, which has a strong muscular wall and pumps blood in pulses, at high pressure into the arteries

The right ventricle pumps blood to the lungs and the left ventricle pumps the blood into the aorta and around the head and body.

The pulse rate is controlled by two sets of nerves which come from the brain. One set slows the heart rate and the others speed it up. This enables you to increase the supply of blood to your body organs when you increase your level of activity. (e.g. to your leg muscles when you run)

Blood Flow

Blood flows through the body with pulsing action. The walls of the aorta contain elastic fibres and muscle fibres which stretch in response to the pulse of blood each time the heart beats.

How does the AbioCor Implantable Replacement Heart work?

The AbioCor Heart is made from titanium metal and a special type of plastic. A rechargeable internal battery allows the patient to be completely free of the external power transmission unit for some period of time. Normally an external power pack transmits power across the skin

Thoracic Unit in Hand
with permission from AbioCor

Two hearts as one

Just like the natural heart, the AbioCor Implantable Replacement Heart consists of two blood pumps. The right chamber supplies blood to the lungs, while the left pump provides blood to other vital organs and the rest of the body. Each of the two pumps is capable of delivering more than eight litrers of blood every minute. The replacement heart is compact (about the size of a grapefruit) and quiet. A stethoscope is required to listen to the "heart sounds."

Blood Flow

The AbioCor system is designed to increase or decrease its pump rate in response to the body's needs. It will generate pulsatile blood flow which safely mimics the heart’s pumping action.The AbioCor also includes an active monitoring system that provides detailed performance feedback and alarms in the event of irregularities.


with permission from AbioCor

Replacement Heart
replaces diseased
ventricles of failing heart

More Info and Images Activities
Frequently asked questions Compare Hearts Quiz
Natural Heart Heart dissection

Patient X-ray

Heart Quiz
Setting up AbioCor Artificial Heart Circulation Quiz
Implant Preparation  
Implanting the AbioCor Artificial Heart Extension lesson