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 Immune System


A Cellular Automata Model written in HTML, Java, and JavaScript
This site requires Netscape 3.0 or better with Java and JavaScript enabled and good processor speed.

-- Please wait until entire document loads before executing simulation --
Loading may require several minutes. In the meantime you may read about Background Information on the Specialized Conduction System or Features of this Automata Model and return to this window after the document has fully loaded.


Design, programming and graphics by:
  Wesley Joe
  wj@acpub.duke.edu
Please send comments and suggestions to the above e-mail address.

Project for BME 204: Measurement and Control of Cardiac Electrical Events
Joseph Cadugan, Karen Knopp, and Wesley Joe
Department of Biomedical Engineering, Duke University
Instructor: Dr. Patrick Wolf
Spring 1997


BACKGROUND INFORMATION
MODEL FEATURES


ONLINE CONFIGURATION OF AUTONOMA MODEL :

Blocked Conductivity:
You may choose a region to be blocked (rendered inexcitable):
SA Node
Bachmann's Bundle
Atrial Internodal Tracts
AV Node
Bundle of His
Right Bundle Branch
Left Bundle Branch
Anterosuperior Fascicle
Inferoposterior Fascicle
Septal Fascicle Fibers

Time Scaling:
Depending on the capabilities of your CPU, you may want to adjust the time scale of the simulation.
Modification of time scale may also aid in analysis of conduction properties
Scale time by a factor of: times
Note: small timescales may yield erroneous results due to limits in computation time and image updating. A factor of at least 10 is recommended. Slower machines (such as PCs/Macs with clock speeds less than 66 MHz) may require time scales as high as 50.

Automaticity Period:
You can adjust the time period when a fiber automatically activates itself, in terms of beats per minute:
SA Node: bpm
AV Node: bpm
Purkinje: bpm

Pacing:
Forced pacing may be set upon a region of tissue at a regular rate:
Tissue region:
 Pacing Rate:
beats per min



. . . . .

References:

Goldschlager, Nora and Mervin J. Goldman. Principles of Clinical Electrocardiography.
  Appleton and Lange, Norwalk, CT: 1989

Netter, Frank H. The CIBA Collection of Medical Illustrations. Volume 5,
   CIBA, New York: 1969


Wesley Joe
5/2/97